Chase Elliott will start in sixth, followed by Ricky Stenhouse Jr. and Brad Keselowski. It was Blaney's third pole in 93 Monster Energy Cup Series starts, and Harvick's best effort in 18 races at Las Vegas. Daytona 500 Champion Austin Dillon, who won the Boyd Gaming 300 NASCAR Xfinity Series race at LVMS in 2015 - is at 75-1.
Cole Custer, a NASCAR Xfinity Series regular gearing up for his premier-series debut, was 25th-fastest at 183.974 miles per hour in the Rick Ware Racing No. 51 Ford.
Sunday's Pennzoil 400 presented by Jiffy Lube will air live beginning at 1 p.m. MT (3 p.m. ET) on Fox, SiriusXM NASCAR Radio Channel 90 and PRN.
"The vehicle is really good", Larson said. I don't know if that had something to do with it or if it was just our adjustments. "We tested here about a month ago and were fast and got a good balance on our auto". At the end of the day I'm sure it was not helping us to get the auto right, because for whatever reason that last run we got really tight in turn three. "The track just went through a lot of changes, transitions I think".
Ryan Blaney earned the pole. He did later return to the track and finished the session 22nd fastest.
Three teams were docked 15 minutes of practice at the end of the session because they were late to Friday's pre-qualifying inspection.