If the IFV drug works as well for humans as it does for mice, science may have found a simple solution for a condition that's caused heartache and pain (both emotional and physical) for countless women.
The team, lead by Paolo Giacobini at the French National Institute of Health and Medical Research, realised levels of anti-Müllerian hormone (AMH) were 30% higher in pregnant women with PCOS than those without.
Beyond helping women to get pregnant, this is an unbelievable breakthrough for those frustrated with the side effects from the condition, because they may at long last have relief.
As such, researchers are hoping to test cetrorelix on women with PCOS by the end of the year.
In the United States, as many as 5 million women are affected by PCOS, but its actual cause has eluded the medicine world even if it was first described by Italian physician Antonio Vallisneri as early as 1721. Other symptoms include multiple cysts on the ovaries, as well as irregular periods and difficulties becoming pregnant.
PCOS affects between 2.2 and 26.7 percent of women in their childbearing years.
"It's a radical new way of thinking about polycystic ovary syndrome and opens up a whole range of opportunities for further investigation", says Norman.
'It's something we've been stuck on for a long time'.
To find out if this excess hormone level was triggering the condition, they injected pregnant mice with anti-Müllerian hormone.
As the mice's female offspring aged they showed signs of polycystic ovary syndrome, suggesting the hormone could be a cause.
Scientists believe they have discovered why polycystic ovary syndrome (PCOS) occurs and affects roughly one in five women.
Irregular periods - which means the ovaries don't regularly release eggs (ovulation).
The condition happens due to elevated androgens (male hormones) in females. They surmised that the excess levels of AMH promoted brain cells in the fetus to produce too much testosterone.
With a new way of looking at PCOS, researchers also thought up a possible treatment for the condition in the form of cetrorelix, an IVF drug that's used to control women's hormones. In fact, many women may be living with PCOS and not even know it.