When asked if they were carrying Novichok with them, both Petrov and Boshirov laughed it off.
Mr Boshirov said: "When your life is turned upside down, you don't know what to do and where to go. We didn't have it", Boshirov said.
Boshirov and Petrov went on to explain that they had also expected to visit other nearby attractions, but their plans were thwarted.
The men, who United Kingdom authorities named as Alexander Petrov and Ruslan Boshirov, said they were in Salisbury in March to see the famous Salisbury Cathedral.
A European arrest warrant has been issued for the two suspects, but British prosecutors say they will not ask Moscow to extradite Russian citizens because Russia's constitution forbids it.
They denied having any Novichok, a deadly Soviet-developed nerve agent, in their possession.
On September 5, British Prime Minister Theresa May informed the country's parliament about the conclusions that investigators looking into the Salisbury incident had come to, saying that two Russians, believed to be GRU agents, were suspected of conspiracy to murder the Skripals.
Putin expressed hope they would come forward and speak publicly.
Britain said it was clear the two men, who appeared on Russia's state-funded RT television, were agents of Russia's GRU military intelligence who carried out the attack, and their interview an example of Russia's "obfuscation and lies".
They said they wanted to go to Stonehenge but were prevented from doing so because there was "muddy slush everywhere" so they got wet and went back to London an hour after arriving, as there was an intermittent weekend train service.
"We know who they are, we have found them". They denied that they carried a bottle of women's perfume where British authorities found traces of Novichok.
Simonyan said the two men contacted her directly and that she had not looked for them personally. They would have questions as to why men have women's perfume in their luggage. "We didn't have it", Boshirov told RT.
Petrov said he heard Putin's statement on the radio and made a decision to contact RT's editor-in-chief.
In the RT interview, the two men said they're not Russian agents, describing themselves as "second-tier businessmen" in the fitness industry. The pair were released from the hospital two months later and moved to a private, secure location.
CCTV footage shows Petrov and Boshirov, who traveled on Russian passports and were previously believed to have used aliases, arriving in the United Kingdom on Friday evening on an Aeroflot flight into London's Gatwick airport. The pair were also picked up by CCTV footage in the vicinity of the Skripal house on the day of the attack, March 4, which is in the opposite direction of the cathedral from the train station.
Britain has said the two suspects were Russian military intelligence officers nearly certainly acting on orders from high up in the Russian state.