"Open please!" one woman said through tears at the final barrier, carrying a baby in her arms.
The migrants say they organized for the long and hard journey on social media, but Washington suspects the group has been organized as a deliberate provocation.
On Friday afternoon, hundreds of the migrants poured through Guatemala's frontier posts towards the closed Mexican border on a bridge spanning the Suchiate River that bisects the two countries, Mexican television footage showed. The migrants intent to claim refugee status but some have raised doubts over who these people really are and whether they are fleeing violence.
Mauro Verzzeletti, a priest who runs the Casa del Migrante shelter in the Guatemalan capital, said about 3,000 people slept there overnight and left around 4 a.m.to continue the journey, adding that "more are arriving".
CNN's Bill Weir was on a bridge that links Mexico and Guatemala Friday, as the caravan of migrants pushed through the border.
Orellana says "the economy in Honduras is awful, there is nothing there".
But there are still many unanswered questions about how this will actually play out once large numbers of migrants arrive.
Manelich Castilla told Foro TV the migrants will enter in an orderly fashion.
As the sun rose, a military helicopter flew along the Mexican side of the river foreshadowing the difficulties they could face. More than 150 members of that group crossed the border and sought asylum.
Jonathan Guzman, who joined the mass procession caravan en route, said he dreams of finding a construction job in Los Angeles.
Jonathan Guzman, a 22-year-old from El Salvador, said he had dreams of working in construction in Los Angeles.
Marcelo Ebrard, Lopez Obrador's pick to become foreign relations secretary after he takes office, said Trump's tweets needed to be understood in the context of the upcoming US midterm elections.
Several of the migrants told The New York Times they hoped to pursue a better life for themselves and their families. Those caught entering the country in what Mexican officials called an "irregular manner", however, will supposedly be detained and deported.
Now, Scalise says that Trump was "clearly ribbing" Gianforte for the incident, claiming that "not one [Trump supporter] harassed the numerous media reporters who were present".
On Wednesday, the president also threatened to cut USA aid to the Northern Triangle countries - Honduras, Guatemala and El Salvador - saying "all payments made to them will STOP (END)!".
Per NBC News, Mexico dispatched an additional 500 federal police to the border with Guatemala ahead of the migrants' arrival. It was at that time that President Trump deployed National Guard troops along the border and threatened to rip up the North American Free Trade Agreement, or NAFTA.
"The president certainly can slow down crossing at legal border crossings where about a million people cross each day".