The embattled British prime minister has faced the biggest test of her premiership after ministers including the Brexit Secretary Dominic Raab and the Work and Pensions Secretary Esther McVey resigned to protest her Brexit plans.
Less than a week before a European Council summit, where EU leaders are due to rubber stamp the Prime Minister's deal, she is braced for fresh attacks from inside and outside her own party.
Raab later told the BBC he would vote against the Brexit deal in parliament, but had not submitted a letter of no confidence in the Prime Minister.
On Sunday, Mrs May said she was aware that the number had not reached 48, while chairman of the Conservative backbench 1922 Committee, Sir Graham Brady also confirmed it had not been hit.
Mrs May said she would travel to Brussels this week to meet European Commission President Jean-Claude Juncker. "It goes alongside the future relationship", she said.
"Replacing me is not going to make the (Brexit) negotiations any easier and it won't change the parliamentary arithmetic", she added.
"The former prime minister reportedly remarked in the early hours of June 24, after the Brexit vote had gone against him, 'Why should I do all the hard s***?'"
May said negotiations were continuing and she meant to go to Brussels and meet European Commission President Jean-Claude Juncker.
Speaking to The News, MEP and former UKIP leader Nigel Farage said: 'This deal is the worst in history and is a trap to keep us stuck inside European Union rules.
Several British newspapers reported that five senior pro-Brexit ministers were working together to pressure Mrs May to change the draft deal, but writing in The Sun on Sunday newspaper, Mrs May said she saw no alternative plan on the table.
"Some politicians get so embroiled in the intricacies of their argument they forget it is not about this theory or that theory or does it make me look good", she noted in an interview for the Daily Mail published this Saturday.
Wendy Morton, Tory MP for Aldridge and Brownhills, has rallied behind the beleaguered PM, pledging her full support for her contentious Brexit deal.
Raab, himself an ardent Brexiteer, attacked May on Sunday, claiming that the prime minister had effectively caved in to European Union "bullying".
Addressing the issue of immigration, a concern for many businesses who fear they will face skills gaps after Brexit, May will promise to introduce "more streamlined application processes" that will "attract the brightest and the best from around the world".
In either circumstance, her version of Brexit, as set out in the withdrawal agreement and future relationship document, would be in doubt.
Johnson also said that Britain should scrap the so-called Northern Ireland backstop, an insurance policy to avoid a return to border checks between the British province and EU-member Ireland in order to avoid "economic and political servitude" to the EU.
Speaking at the same conference, opposition Labour leader Jeremy Corbyn will describe the deal as "a botched, worst-of-all-worlds deal which is bad for Britain, leaving the country in an indefinite halfway house without a real say".
"If MPs (legislators) reject the deal, they will simply take us back to square one".
The UK will now have a status that is more akin to that of Canada, Japan, and the United States, which allows for limited access to the EU financial market, but this can be modified if both the Britsh and European authorities agree.